Glen Rhodes

AI | Data & Analysis | Machine Learning | Tech

Contrarian take on AlphaGenome 2 release as a signal that the highest-leverage builder opportunities in 2027-2028 are in biology and science, not software productivity
ByGlen Rhodes November 11, 2026

The Builder Opportunity Nobody Is Talking About Most builders in the AI space right now are optimizing for the wrong signal. They’re watching token prices drop, reasoning benchmarks climb, and coding assistants ship faster. That’s real progress. But I think 2027 and 2028 belong to something else entirely, and AlphaGenome 2 is the clearest evidence…

Read More Contrarian take on AlphaGenome 2 release as a signal that the highest-leverage builder opportunities in 2027-2028 are in biology and science, not software productivity
AI | Data & Analysis | Machine Learning | Tech

Claude Fable 5.2 release and the growing gap between public frontier models and internal lab capabilities as a production architecture risk
ByGlen Rhodes November 10, 2026

The Model You Just Got Is Already Obsolete Claude Fable 5.2 dropped on November 9th, and I want to talk about something the press releases won’t say directly. The name change from version numbers to “Fable” is not cosmetic. Anthropic is telling you, in the quietest way possible, that the old mental model of sequential…

Read More Claude Fable 5.2 release and the growing gap between public frontier models and internal lab capabilities as a production architecture risk
AI | Data & Analysis | Machine Learning | Tech

OpenAI GPT-6 Cyber launch and what gated specialized model tiers mean for builders in production security tooling
ByGlen Rhodes November 9, 2026

GPT-6 Cyber and the End of Security Theater The AI industry has spent two years pretending it can build powerful reasoning and code models without enabling offensive security capability. GPT-6 Cyber is OpenAI finally dropping that pretense, and I think it’s the most honest product decision any frontier lab has made in this space. Let…

Read More OpenAI GPT-6 Cyber launch and what gated specialized model tiers mean for builders in production security tooling
AI | Data & Analysis | Machine Learning | Tech

Hot take on US Center for AI Safety reporting to the White House and what structural loss of independence means for builders relying on government oversight as a credibility signal
ByGlen Rhodes November 8, 2026

The Oversight Illusion There’s a sentence buried in recent reporting that I keep coming back to: staff at the US Center for AI Safety are now reporting directly to the White House. If you read that and moved on, I’d argue you missed the most consequential AI governance story of the month, more consequential than…

Read More Hot take on US Center for AI Safety reporting to the White House and what structural loss of independence means for builders relying on government oversight as a credibility signal
AI | Data & Analysis | Machine Learning | Tech

Critique of contradictory AI productivity time-savings data and the hidden cost shift from doing to verifying in AI-assisted workflows
ByGlen Rhodes November 7, 2026

The Productivity Illusion: What AI Time-Savings Data Actually Tells Us Everyone in enterprise tech right now is pointing at AI productivity numbers like they’re a winning lottery ticket. The problem is nobody can agree on what the numbers say. CIO ran a piece in early November pulling together the actual research on AI time savings,…

Read More Critique of contradictory AI productivity time-savings data and the hidden cost shift from doing to verifying in AI-assisted workflows
AI | Data & Analysis | Machine Learning | Tech

METR assessment that Anthropic is doubling model capability improvement rate, and what accelerating model velocity means for production system architecture
ByGlen Rhodes November 6, 2026

The Floor Keeps Rising: What METR’s Anthropic Assessment Means for Production Architecture METR published something last week that deserves more attention than it’s getting. Their independent assessment, released November 5th, found that Anthropic is improving model capabilities on well-specified tasks at roughly twice the rate it was achieving between March 2024 and October 2025. METR…

Read More METR assessment that Anthropic is doubling model capability improvement rate, and what accelerating model velocity means for production system architecture
AI | Data & Analysis | Machine Learning | Tech

Andrej Karpathy joining Anthropic as a signal that interpretability is becoming the central problem in production AI systems
ByGlen Rhodes November 5, 2026

Andrej Karpathy Just Told You Where AI Is Going There are personnel moves that signal prestige, and there are personnel moves that signal direction. Karpathy joining Anthropic is the second kind, and I think a lot of people are reading it too casually. This is not a typical talent acquisition story. Why Karpathy Matters Beyond…

Read More Andrej Karpathy joining Anthropic as a signal that interpretability is becoming the central problem in production AI systems
AI | Data & Analysis | Machine Learning | Tech

Pennsylvania AI Deceptive Advertising Act (Act 99 of 2026) and what mandatory disclosure requirements mean for builders with AI-generated content pipelines
ByGlen Rhodes November 4, 2026

Pennsylvania Just Made AI Disclosure Law. Are Your Ad Pipelines Ready? If you’re shipping AI-generated ad creative and you have any users, customers, or distribution touching Pennsylvania, you now have a legal obligation you may not have planned for. This isn’t a draft. It’s not a proposed rule sitting in committee. Governor Josh Shapiro signed…

Read More Pennsylvania AI Deceptive Advertising Act (Act 99 of 2026) and what mandatory disclosure requirements mean for builders with AI-generated content pipelines
AI | Data & Analysis | Machine Learning | Tech

Hot take: Mistral Large 4 launch exposes the unspoken ownership risk builders take on when choosing open models for high-stakes agentic systems
ByGlen Rhodes November 3, 2026

Mistral Large 4 Just Reminded Everyone That Open Models Come With a Hidden Bill The benchmarks are clean. The positioning is sharp. Mistral’s Large 4 launch calls it the best open model for agentic coding and cyber defense, and from a raw capability standpoint, the numbers back that up. But buried in the Fortune coverage…

Read More Hot take: Mistral Large 4 launch exposes the unspoken ownership risk builders take on when choosing open models for high-stakes agentic systems
AI | Data & Analysis | Machine Learning | Tech

Prediction: Mainstream AI adoption doubling in rural populations signals a design reckoning for builders still optimizing for technically sophisticated users
ByGlen Rhodes November 2, 2026

AI Is Coming for the Design Assumptions You’ve Been Ignoring Here is the number that stopped me cold this week. AI use among rural Nebraskans doubled in two years. Not in San Francisco. Not among enterprise teams with dedicated AI procurement budgets. In rural Nebraska. The 2026 Nebraska Rural Poll, released October 28th by the…

Read More Prediction: Mainstream AI adoption doubling in rural populations signals a design reckoning for builders still optimizing for technically sophisticated users